Organic Chemistry Is Awesome

Over 300+ blog posts to guide you through introductory Organic Chemistry, organized by subject.

08 Substitution Reactions
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Eric E.

Saint Louis University

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Kailey N.

California State University Long Beach

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Chris M.

McMurdo Station, Antarctica

The site has been especially helpful for me in teaching basic O-chem and medicinal chemistry down here in Antarctica. (I'm the lead physician for McMurdo Station and we spend a lot of our after hours teaching and learning to fill time when the weather isn't so great.) From the bottom of the world - thanks!

Marie B.

Florida Atlantic U.

Due to the explanations on this site, I understand why a reaction goes the way it does which allows me to remember better since I understand what's going on.

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Colorado State University

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Binghampton U.

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Fordham U.

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University of South Florida

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Wayne State University

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Augusta U.

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Duke U.

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University of Pittsburgh

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St. Joseph's University

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University of Buffalo

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Cal State East Bay

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Virginia Commonwealth University

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Wright State University

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Cincinnati Public High School

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Manuel E. (with Nobel Laureate Kip Thorne)

East Los Angeles College

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Carmen T.

University of Connecticut

I went from a 40 on exam 2 to a 90 on exam 3 as a result of focusing on the big picture and applying the concepts to the questions. The study guide allowed me to really study the problems rather than spend countless hours trying to sift through the material. I also ended up with a B+ in the class!

Courtney E.

Central Washington University

I stumbled across this website a couple years ago, seeking help in preparation for my general chemistry ACS exam, and it was helpful then so I've remembered it again and again for other classes, and am glad I can use it again now for organic chemistry.

Kaitlyn M.

Penn State University

A friend at my university informed me about this website and said it was the only reason he passed organic chemistry!

Corbin K.

Utah State University

I love everything I've used so far. I used the reaction guide for O Chem 1, and it saved my butt.


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Tara D.

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Michelle T.

Simon Fraser University

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Morgan M.

West Chester University

I recently purchased the organic chemistry guide. I finally understand why things are doing what they are doing. I wish I would've had this numerous organic chemistry attempts ago.

Luke D.

LaMar University

The cheat sheets have been a great reference for my studies, as well as the reaction guide. Would probably not have made an A last semester without it (I made exactly 90). I did it with the more difficult organic professor too!

Abby M.

Lee University

I made an A in my Organic 2 class - this website was an invaluable resource!! Thanks so much.

Zina Z.


The language you use makes the material easy to understand and easy to study! Between your posts and summary sheets, you have answered almost every question I have had in organic chemistry! MOC is such a lifesaver (and grade-saver)!

Case Studies Of Successful Students

From The Blog

James Ashenhurst

Founder, Master Organic Chemistry

After doing a Ph. D. in organic synthesis at McGill and a postdoc at MIT, I applied for faculty positions at universities during the Great Recession. It didn’t work out. But having seen first-hand how many people struggled with the subject (including myself when I took it as an undergraduate) I thought there was a need for an online organic chemistry resource that had all the rigor of a traditional textbook, but was more approachable and accessible.

Drawing on the experience of thousands of hours spent tutoring students 1-on-1, as well as dozens of case studies, Master Organic Chemistry aims to fill in some of the conceptual gaps that aren’t traditionally covered by textbooks, and provide a friendly, logical and thorough pathway for learning introductory organic chemistry.